Fig. 6: Histological studies of inflammation in brain tissues. | Nature Communications

Fig. 6: Histological studies of inflammation in brain tissues.

From: Inflammation-free electrochemical in vivo sensing of dopamine with atomic-level engineered antioxidative single-atom catalyst

Fig. 6

a Histological comparison of brain tissues from untreated rats and rats after 8-hour acute implantation of bare or Fe1/NC-900-modified CFE in NAc (n = 3, for each group). Tissues are labeled for astrocytes (green), microglia (magenta) and nuclei (blue). Scale bar, 50 µm. Fluorescence intensities of astrocytes (b) and microglia (c) in brain tissues from untreated rats (blue line) and rats after 8-h acute implantation of bare CFE (gray line) and Fe1/NC-900-modified CFE (red line) (n = 3, for each group). The distance was measured from the image center for the control group and from the implantation center for the bare and Fe1/NC-900-modified CFE groups. The data were presented as mean ± SEM. Quantitative analysis of ELISA for IL-6 (d), TNF-α (e), and IL-1β (f) in brain tissues from untreated rats (blue column) and rats after 8-hour acute implantation of bare (gray column) and Fe1/NC-900-modified (red column) CFE (n = 3, for each group). The data were presented as mean ± SEM and p values were provided in the figures using one-way analysis of variance (ANOVA). Source data are provided with the paper.

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