Fig. 1: The univariate signatures of basal ganglia volumes indicate high heritability and significant phenotypic and genetic correlations.
From: The genetic landscape of basal ganglia and implications for common brain disorders
A Heritability of basal ganglia volumes (n = 34,794), where the numbers depict SNP-heritability estimates (h2). In the plot, the dots represent mean heritability for each subregion of the basal ganglia, while the error bars represent the standard error (SEM): Putamen in pink (h2 = 0.296, SEM = 0.0.026), Pallidum in light blue (h2 = 0.253, SEM = 0.021), Caudate in red (h2 = 0.342, SEM = 0.025), Accumbens area in green (h2 = 0.261, SEM = 0.02) and whole basal ganglia in gray (h2 = 0.304, SEM = 0.026). B LD-score regression-based genetic correlations (in lower-right section) and phenotypic correlation (in upper-left section) between each pair of regions, using the univariate GWAS summary statistics.
