Fig. 1: Overall structures of histamine receptors in complex with respective G proteins.
From: Structural basis of ligand recognition and activation of the histamine receptor family
a–d Cryo-EM density maps (middle) and corresponding models (bottom) of Histamine-bound H1R-Gq (a), Histamine-bound H2R-Gq/Gs (b), Histamine- or Imetit-bound H3R-Gi, and Proxyfan-, or Immethridine-bound H3R-Go (c), Immepip-, or Histamine-bound H4R-Gi (d). Cryo-EM density maps of respective ligands have been shown in gray dotted boxes (top).
