Fig. 2: Protein composition of the serum protein corona adsorbed on GOs.
From: Selective regulation of macrophage lipid metabolism via nanomaterials’ surface chemistry
a Classification of components on three types of GOs (L-GO, M-GO and H-GO) by biological function. The pie chart indicates the relative abundance of coronal proteins in six categories: apolipoproteins, complements, acute phase, immunoglobulins, coagulation factors, and others. Albumin, due to its highest abundance in serum, is classified as an individual category. b Comparison of functional protein groups on the surface of graphene oxides. c Enrichment factor of apolipoproteins on different graphene oxide nanosheets. The enrichment factors (b, c) represent the comparison of protein or protein group abundance on GOs to that in the serum (coronal complex of GOs/serum). Protein compositions are identified through manual search using the Human Database via the UniProt website. Data are presented as mean ± standard deviation of triplicate biological samples (n = 3). Proteomics data are presented in Supplementary Data 1. Source data are provided as a Source Data file.
