Fig. 3: Mouse PK data for compound PDEi2.

A Time courses of total drug concentration determined in plasma with single dose IV and oral administration at indicated doses. B Time courses of total drug concentration determined in washed intestinal tissue segments with single dose 10 mg/kg oral administration. Data for (A) and (B) are mean and SEM (n = 3 mice per experimental group where SEM shown; n = 2 mice per group where no SEM shown). Source data for (A) and (B) are provided as a Source Data file.