Fig. 3: Comparison of the ATP-bound and NF449-bound P2X1 receptor.
From: Structural insights into the human P2X1 receptor and ligand interactions

A Overlay of the ATP-bound P2X1 receptor (red) and NF449-bound P2X1 receptor (blue) at the orthosteric binding site, illustrating movement in secondary structure with arrows. B Overlay of the ATP-bound P2X1 receptor (red) and NF449-bound P2X1 receptor (blue) at the lower body and transmembrane domain, illustrating movement in secondary structure with arrows.