Fig. 3: Distribution analysis of peripheral subunits in intact OGDHc.
From: Molecular architecture of the mammalian 2-oxoglutarate dehydrogenase complex
a Relative position of a E1o group to one vertex. The points represent individual projections of the mass of E1o along the Z-axis. The positive direction of the z-axis is defined as the direction from the origin of the core to the center of the vertex. The characteristics of 3-fold symmetry in the x-y plane are demonstrated. b Orientation of E1o around the core. E1o prefers a tilt of 30° relative to the E2 center-E1o center line. c Comprehensive distance and angle distribution of E1o. The horizontal axis and the vertical axis represent the angles and distance of each E1o relative to E2o. The shade of color represents the frequency of the corresponding distance and angle. d Relative position of E3 to one vertex. e Orientation of E3 around the core. E3 distributes diffusely in the tilt of 60–120°. f Comprehensive distance and angle distribution of E3. g Illustration of angle tilt of E1o and E3’s orientation in the complex. The orientation angle is defined as the angle between the C2 axis of the E1o/E3 and the E2o-E1o/E3 line.
