Fig. 1: Proposed deep spatiotemporal prior for the uncoupling of sensor kinetics (DUSK).
From: Deep-prior ODEs augment fluorescence imaging with chemical sensors

A Left: Measured fluorescence with GCaMP sensors that bind to Ca2+. Right: Predicted fluorescence with the proposed method. B DUSK recovers the spatiotemporal distribution of a chemical species. Left: Our method recovers the Ca2+ concentration by fitting the fluorescence measurements in consistency with the chemical reaction (top) and with the help of a deep-image prior (bottom). The predicted (denoised) fluorescence (A, right) is a byproduct of this. Right: Ca2+ distribution recovered by DUSK.