Fig. 4: Using the EV-METRIC to evaluate reporting transparency. | Nature Communications

Fig. 4: Using the EV-METRIC to evaluate reporting transparency.

From: Mapping bacterial extracellular vesicle research: insights, best practices and knowledge gaps

Fig. 4

a Evolution of average EV-METRIC (%) for EEV (cyan) and BEV (purple) studies from 2015 to 2021. Violin and dot plot show EV-METRIC for each included BEV study; number of studies per year are indicated on the x-axis. The highest EV-METRIC is 87%; 36% achieve an EV-METRIC of 0%. be Radar charts representing the percentage of experiments that adhere to each of the respective EV-METRIC components according to b source type, c gram staining of studied bacteria, d species type (top three studied species E. coli S. aureus, and P. aeruginosa), and e domain (included experiments for BEVs compared to EEVs). BEV bacterial extracellular vesicle, EEV eukaryotic extracellular vesicle, E. coli Escherichia coli, EM electron microscopy, Pseudomonas aeruginosa, S. aureus Staphylococcus aureus.

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