Fig. 2: Manhattan plot for the GWAS-by-subtraction derived non-IOP-dependent component of POAG.
From: GWAS-by-subtraction reveals an IOP-independent component of primary open angle glaucoma

Plot of the −log10(P-value) associated with Wald’s test (two-sided) of the beta coefficient for the non-IOP-dependent component of POAG for all SNPs, ordered by chromosome and base position. The threshold for genome-wide significance after considering of multiple tests is indicated by the red dashed line (P = 5.0 × 10−8).