Fig. 4: Genetic correlations of the non-IOP-dependent component of POAG, the IOP-dependent component of POAG, and POAG itself with other traits.
From: GWAS-by-subtraction reveals an IOP-independent component of primary open angle glaucoma
The dots represent genetic correlations estimated using LDSC. Correlations with the non-IOP-dependent component of POAG are shown in red and with the IOP-dependent component of POAG in dark blue. Error bars represent 95% confidence intervals (CIs). Closed circles indicate statistically significant genetic correlation (LDSC uncorrected P < 0.05, two-sided test). Full results, study details and sample size are reported in Supplementary Data 8. Body mass index (BMI); systolic blood pressure (SBP), diastolic blood pressure (DBP); pulse pressure (PP); low-density lipoprotein (LDL); high-density lipoprotein (HDL); coronary artery disease (CAD); chronic kidney disease (CKD). Source data are provided on figshare (https://doi.org/10.6084/m9.figshare.25045220).
