Fig. 6: Structure of putative OF conformation of PCAT1 in lipid Nanodsics. | Nature Communications

Fig. 6: Structure of putative OF conformation of PCAT1 in lipid Nanodsics.

From: Conformational cycle of a protease-containing ABC transporter in lipid nanodiscs reveals the mechanism of cargo-protein coupling

Fig. 6

Comparison of the putative OF conformation of PCAT1 in detergent micelles (gold) with the OF conformation of the transporter core, PCAT1_CC, in lipid nanodiscs (teal). A Side view of the two structures highlighting the opening of the latter to the outer leaflet of the membrane. B Extracellular view identifying the movement of individual helices.

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