Fig. 8: DEER analysis of the conformational dynamics of the core transporter.

DEER distance distributions of the core transporter in lipid nanodiscs under turnover conditions (solid teal traces). Experimental and predicted distance distributions are shown in solid and dashed lines respectively. Except for 307 and 498, the distributions under turnover conditions are superimposable with those bound to ADP/Mg2+ (solid purple traces).