Table 1 Relative binding free energy of ATP with respect to ADP in kcal/mol in the presence (ΔΔG_Mg) and absence (ΔΔG_noMg) of Mg2+ and their difference (ΔΔG_Mg-ΔΔG_noMg) in the outward-facing state

From: Conformational cycle of a protease-containing ABC transporter in lipid nanodiscs reveals the mechanism of cargo-protein coupling

 

MgATP/MgADP (\(\Delta \Delta {G}_{{Mg}}\))

ATP/ADP (\(\Delta \Delta {G}_{{noMg}}\))

\(\Delta \Delta {G}_{{Mg}}-{{\Delta }}\Delta \Delta {G}_{{noMg}}\)

PCAT1

21.86\(\pm\)0.75

3.36\(\pm\)0.78

18.50\(\pm\)1.1

MsbA

−6.50\(\pm\)0.81

−18.87\(\pm\)0.48

12.37\(\pm\)0.94

Sav1866

−5.40\(\pm\)0.87

−24.88\(\pm\)0.30

19.48\(\pm\)0.92

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