Table 1 Optimization of the reaction conditions
From: Organoelectrocatalytic cyclopropanation of alkenyl trifluoroborates with methylene compounds
| ||
|---|---|---|
entry | variation from standard condition | Yield [%]a |
1 | none | 94b |
2 | C( + )/C(-) instead of C(+)/Pt(-) | 78 |
3 | C(+)/Zn(-) instead of C(+)/Pt(-) | 49 |
4 | GF(+)/Pt(-) instead of C(+)/Pt(-) | 85 |
5 | C(+)/Ni(-) instead of C(+)/Pt(-) | 90 |
6 | CH3OH, DMF, DMSO, or CH2Cl2 instead of CH3CN | 0 |
7 | nBu4NBF4 instead of nBu4NPF6 | 73 |
8 | no nBu4NPF6 | 76 |
9 | 1.2 equiv 2 | 62 |
10 | 3.0 equiv 2 | 76 |
11 | 1.5 h | 51 (42)c |
12 | 4 h | 70 |
13 | 5 mA | 52 (44)c |
14 | 10 mA | 77 |
15 | no H2O | trace |
16 | no PhSPh | 3 |
17 | no electricity | 0 (100)c |
