Fig. 4: Desymmetrization of silacyclohexadienones via Rh-catalyzed oxidative Heck reaction with intramolecular hydrogen transfer. | Nature Communications

Fig. 4: Desymmetrization of silacyclohexadienones via Rh-catalyzed oxidative Heck reaction with intramolecular hydrogen transfer.

From: Carbon-silicon-switch effect in enantioselective construction of silicon-stereogenic center from silacyclohexadienones

Fig. 4

a Scope of silacyclohexadienones. b Scope of organoboronic acids. Reaction conditions (condition B): 1 (0.20 mmol), RB(OH)2 (0.40 mmol), [RhCl(coe)2]2 (5 mol% Rh), (R)-DTBM-binap (6 mol%), KOH (0.02 mmol), and dioxane (1.0 mL) at 60 °C for 12 h.

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