Table 1 Basic characteristics of the participants in the three national biobanks
Biobank | UK Biobank | Estonian Biobank | THL Biobank* |
|---|---|---|---|
Number of participants | 477,078 | 190,785 | 32,354 |
Age at blood sample (median, [IQR]) | 58.0 [50.0–63.0] | 43.0 [31.0–56.0] | 51.0 [39.0–61.0] |
Females (N (%)) | 260,253 (54.6) | 125,565 (65.8) | 17,248 (53.3) |
Body mass index (kg/m2; median, [IQR]) | 26.7 [24.1-29.8] | 25.3 [22.4-29.0] | 26.2 [23.6-29.4] |
Smoking prevalence (%) | 10.5 | 18.3 | 34.7 |
Cholesterol lowering medication (%) | 17.4 | 10.1 | 10.7 |
Follow-up time (median, [IQR]) | 11.8 [11.0–12.5] | 3.2 [2.9–3.7] | 13.8 [8.8–15.2] |
Recruitment period | 2006–2010 | 2002–2021 | 1997–2012 |
Number of incident events 4 years after baseline visit | |||
Myocardial infarction | 2753 | 441 | 304 |
Ischemic stroke | 1791 | 517 | 281 |
Intracerebral hemorrhage | 468 | 117 | 47 |
Lung cancer | 1259 | 180 | 48 |
Type 2 diabetes | 3649 | 916 | 484 |
Chronic obstructive pulmonary disease | 3716 | 732 | 168 |
Alzheimer’s disease | 180 | 58 | |
Vascular and other dementia | 326 | 175 | 24 |
Depressive disorders | 4921 | 2774 | |
Alcoholic liver disease | 322 | 109 | 33 |
Cirrhosis of the liver | 321 | 69 | 8 |
Colon and rectum cancers | 1965 | 293 | 60 |
