Fig. 2: Two nearly identical VgrG spike proteins export two evolutionarily unrelated H2-T6SS effectors. | Nature Communications

Fig. 2: Two nearly identical VgrG spike proteins export two evolutionarily unrelated H2-T6SS effectors.

From: A widespread accessory protein family diversifies the effector repertoire of the type VI secretion system spike

Fig. 2

A Schematic representation of three DUF4123 gene clusters in Pseudomonas aeruginosa strain PA14. B, C Outcome of intraspecific growth competitions between the indicated P. aeruginosa PA14 donor and recipient strains. The competitive index is calculated as a change (final/initial) in the donor-to-recipient ratio. Error bars represent mean values +/− SEM, n = 3 biological replicates. Asterisks indicate statistically significant differences in the competitive indices between indicated donor and recipient strain (p < 0.05). Differences between groups were calculated using an ordinary one-way ANOVA with multiple comparisons against the parent strain. p-value in panel B is 0.03. In panel C, the p-value for the mean difference between the parent and ∆vgrG6 competed against the ∆ptx2∆pti2 strain is 0.04. In panel C, the p-value for the mean difference between the parent and the ∆vgrG14 strain competed against the ∆rhsP2∆rhsI2 recipient is 0.0059. All other p-values are not significant.

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