Fig. 5: Morphological stereotypy and diversity in neuronal arbors.
From: Neuronal diversity and stereotypy at multiple scales through whole brain morphometry
A Matrix visualization of normalized morphological features of axonal arbors for 20 soma-types (s-types). The blue and red dots represent the features of proximal and distal axonal arbors respectively, and the ordering of arbors (A1, A2, A3) was determined based on their distance-to-soma values. The top left sketch is an exemplar illustration of the categorization of proximal and distal arbors, and their orderings. The arbor types were determined by their distances from the max density compartment to somas, where a max density compartment refers to the compartment containing the maximal number of compartments within a 20 ÎĽm radius. The histogram on the right displays the average percentage of proximal arbors for each s-type. The parenthetical number after region name indicates the number of neurons in that region. B Matrix visualizations of normalized morphological features of dendritic arbors (top left) and axonal arbors (bottom left) for extratelencephalic (ET) and intratelencephalic (IT) neurons of 4 cortical regions. The top-right component shows representative dendritic morphologies for each region and projection type. The bottom-right component shows horizontal and sagittal projections of axonal arbors for ET (left) and IT (right) neurons embedded in the CCFv3. C Axonal arbor morphologies and projection distributions of lamination subtypes of cortical SSp neurons across cortical laminations. Left, the projection distribution across cortical laminations and their representative structures. The central circular heatmap shows the projection strengths across cortical laminations (radial vectors). The dendrogram in the center of the plot shows hierarchical clustering based on the projection strength heatmap. Two outer layers in the plot show representative examples of proximal and distal axonal arbors. The number of neurons of each subtype is specified in parentheses. Right, matrix visualization of the projection strength for lamination subtypes (top) and s-types (bottom).
