Table 1 Subject characteristics

From: OSGEP regulates islet β-cell function by modulating proinsulin translation and maintaining ER stress homeostasis in mice

Characteristic

Discovery cohort

Validation cohort

T2DM

Control

p value

T2DM

Control

p value

N

234

285

 

228

228

 

Sex

Male

146

133

0.001

103

95

0.45

Female

88

147

125

133

Age (years)

58.80 ± 11.83

44.50 ± 11.19

<0.001

48.93 ± 14.41

41.65 ± 11.57

<0.001

BMI (kg/m2)

24.53 ± 3.21

24.23 ± 3.16

0.710

24.44 ± 4.05

-

-

Fasting plasma glucose (mmol/L)

13.73 ± 6.35

5.17 ± 0.99

<0.001

10.64 ± 10.29

4.59 ± 0.39

<0.001

  1. Age, BMI, and Fasting plasma glucose are presented as the mean ± SD. Chi-square test was used to analysis sex. Nonparametric Mann-Whitney U test was used to analyze Age, BMI, and Fasting plasma glucose.
  2. T2DM Type 2 diabetes mellitus, BMI body mass index.
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