Table 2 Rs74512655 association with T2DM

From: OSGEP regulates islet β-cell function by modulating proinsulin translation and maintaining ER stress homeostasis in mice

SNP

Chromosome

Position

MAF

Discovery

Validation

Combine

Kyoko et al29.

OR (95%CI)

p value*

OR (95%CI)

p value#

OR (95%CI)

p value*

OR (95%CI)

p value

rs74512655 (G > C)

chr14:20449766

Intron

0.1806

0.593 (0.387–0.906)

0.016

0.636 (0.435–0.928)

0.019

0.621 (0.472–0.817)

0.001

0.939 (0.886–0.995)

0.033

  1. *Multi-factor binomial Logistic Regression Analysis with adjusted for sex and age.
  2. #Multi-factor binomial Logistic Regression Analysis with adjusted for age.
  3. p value: Statistical methods used to calculate GWAS outcomes are reported in the original publications.
  4. SNP single-nucleotide polymorphisms, MAF minor allele frequency, OR Odds ratio, CI Confidence Interval.
Back to article page