Fig. 2: AR-MPXV5 induces an antigen-specific CD4+ T cell response in cynomolgus macaques.
From: A penta-component mpox mRNA vaccine induces protective immunity in nonhuman primates
MPXV antigen-specific CD4+ cells secreting IFN-γ, IL-2, and IL-4 were determined by flow cytometry 42 days post-initial immunization. n = 3 independent biological replicates (Sham), n = 4 independent biological replicates (AR-MPXV5). Data are shown as the mean ± SEM. Statistical differences were analyzed by using two-way ANOVA. *P < 0.05, **P < 0.01. The exact P values are: P = 0.0013 (M1R, IL-2), P = 0.0195 (E8L, IL-2) and P = 0.0037 (B6R, IL-2). Source data are provided as a Source Data file.
