Fig. 2: Directional preferences of LEC cells in 1-dimensional shuttling tasks.

a Left, four example LEC neurons showing directionally selective firing on the circular track. Shaded red and blue colors denote the mean ± SEM for counterclockwise and clockwise movement, respectively. The black line denotes the difference between the firing rates for the two directions. Colored lines and dotted lines are thresholds for detecting pointwise and family-wise significant regions, respectively. Bold color lines at the top denote regions of significant direction selectivity. Right, four neurons with direction selectivity in linear track paradigm. Same conventions as for the circular track (left). b Distribution of locations with peak direction selectivity index (see Methods) for each cell on the circular track. c Same as Fig. 3b for the linear track. d Four example LEC neurons with strong distance coding in the circular track task. All four cells fired comparably depending on the distance from the start of the journey. e Same as panel (d) for four cells in the linear track task. f Left: sorted spatial rate maps for the two directions in the circular track task. Right: population correlation matrix between the two directions. A high correlation in the main diagonal (bottom left to top right) indicates consistent firing at the same location for the two directions, whereas a strong signal in the minor diagonal (top left to bottom right) indicates consistent firing at the same journey distance from the track ends. g Left, the observed mean correlation of bins along the minor diagonal of the correlation matrix (i.e., from top left to lower right showing the correlation between the same distances from the start position in both directions) is shown as the red line and the null distribution is simulated with a permutation analysis. Right, the observed correlation difference (the red line) and the null distribution comparing the distance coding from the starting position (the first 4 bins) and the end position (the last 4 bins). h, i Same as panels (f) and (g) for the linear track task. Source data are provided as a Source Data file.