Fig. 3: Transcriptomic characterization of Rec and NonRec NSCLC groups. | Nature Communications

Fig. 3: Transcriptomic characterization of Rec and NonRec NSCLC groups.

From: Multi-omics analyses reveal biological and clinical insights in recurrent stage I non-small cell lung cancer

Fig. 3

a Volcano plot showing DEGs in Rec and NonRec LUAD groups (DESeq2 method). b Volcano plot showing DEGs in Rec and NonRec LUSC groups (DESeq2 method). c EMT and angiogenesis scores between Rec and NonRec LUAD groups. d EMT and angiogenesis scores between Rec and NonRec LUSC groups. e KEGG and GO pathway enrichment between Rec and NonRec LUAD groups (hypergeometric distribution). f KEGG and GO pathway enrichment between Rec and NonRec LUSC groups (hypergeometric distribution). g The naïve, exhausted, and cytotoxic states assessment derived from ssGSEA scores between Rec (n = 23) and NonRec (n = 22) groups. P-values are obtained from GSEA (c, d) and unpaired two-sided Wilcoxon ranked-sum test (g). The boxes indicate the median value, interquartile range, with whiskers extending from the box boundaries to upper/lower quartile ± 1.5 interquartile range. Source data are provided as a Source Data file.

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