Fig. 2: Embryos infected with ZIKV develop subcutaneous edema.
From: Epidemic Zika virus strains from the Asian lineage induce an attenuated fetal brain pathogenicity
a Picture showing representative E14.5 mouse embryos with mild (arrow left embryo) and severe (arrow right embryo) subcutaneous edema. b Percentage of mouse embryos presenting subcutaneous edema at E13.5 after infection with either pre-epidemic (n = 17 in total) or epidemic (n = 33 in total) ZIKV strains. c, d Percentage of mouse embryos presenting subcutaneous edema at E14.5 (c) or E15.5 (d) after infection with either pre-epidemic (n = 43 and n = 31, respectively, in total) or epidemic (n = 82 and n = 53, respectively, in total) ZIKV strains. Statistical significance of differences was determined by the two-sided Fisher’s exact test (b–d). Source data are provided as a Source Data file.
