Table 1 Functional annotation of putative pilus proteins

From: A conserved pilin from uncultured gut bacterial clade TANB77 enhances cancer immunotherapy

Protein index

Protein length (aa)

Root level eggNOGa

Protein domaina

TMH; signal peptidea

Sequence homology

Structural homology

927

358

COG3745

-

1 TMH

-

CpaB

928

231

COG1192

-

-

-

TadZ

929

280

COG1192

IPR027417

-

-

CpaE

930

640

COG4962

IPR001482

1 TMH

TadA; CpaF (of Roseburia or Paenibacillus)

TadA

931

693

2DBEG

-

8 TMH

-

TadC (First half); TadB(Second half)

932

165

-

PS51257

1 TMH

-

-

933

170

-

-

1 TMH

-

-

934

143

-

-

1 Signal peptide

-

-

935

146

-

-

1 TMH

-

-

936

237

-

-

1 TMH

-

-

937

178

2A0CU

-

1 TMH

-

-

938

621

28K4V

-

1 TMH

-

TadE; PilV (Partial)

  1. aDescription and abbreviation.
  2. COG3475: Flp pilus assembly protein CpaB.
  3. COG1192: ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ.
  4. COG4962: Pilus assembly protein, ATPase of CpaF family.
  5. 2DBEG: Unknown function.
  6. 2AOCU: Unknown function.
  7. 28K4V: Unknown function.
  8. IPR027417: P-loop containing nucleoside triphosphate hydrolase.
  9. IPR001482: Type II/IV secretion system protein.
  10. PS51257: Prokaryotic membrane lipoprotein lipid attachment site profile.
  11. TMH Transmembrane helix.
  12. Genus name is italicized.
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