Fig. 3: Single chromosome fusion causes minor readjustments of the chromosome position in the nucleus.
From: Visualization of chromosomal reorganization induced by heterologous fusions in the mammalian nucleus
a Averaged chromosome distance between all chromosomes in O48 and ROB-O48 cell lines. Red, chromosomes are close to each other; blue, chromosomes are distanced. 100 models for each sample repeat. b Percentage changes of chromosome distance between each chromosome pair in R1n13, R2n6 and R5n17 cell lines. Except for the fused chromosomes, chromosome distances were either decreased (blue) or increased (red) slightly. c Distribution of chromosome distance disturbances in ROB-O48 cell lines, 190 chromosome pairs. d Volcano plot of chromosome distance percentage change and p-value in R1n13, R2n6 and R5n17 cell lines. Cyan (*), p < 0.05, |PC | > 0.2; yellow (**), p < 0.01, |PC | > 0.2; red, p < 0.05 only; gray, p > 0.05; two-sided t-test; round dots, distances involved fused chromosomes; triangle dots, the distance between non-fused chromosomes; numbers of chromosome pair in each section are indicated. e, f Chromosome distance between chr17 and chr18/chr19 in O48 and R5n17 cell lines (3 samples, 100 models each). p-values were indicated, two-sided t-test.
