Fig. 2: Structure of the ASFV RNAP M1249L C-tail occupied complex 1 (MCOC1) and comparison with known RNAPs. | Nature Communications

Fig. 2: Structure of the ASFV RNAP M1249L C-tail occupied complex 1 (MCOC1) and comparison with known RNAPs.

From: Structural basis of RNA polymerase complexes in African swine fever virus

Fig. 2

a Overall structure of the ASFV MCOC1, shown in cartoon depiction with helices depicted as cylinders. Subunits are colored by chains. The active site magnesium and zinc ions are shown as red and cyan spheres, respectively. b Comparison of subunit compositions among ASFV RNAP, H. sapiens Pol II (PDB: 5IYD8), and VACV RNAP (PDB: 6RIC16). These structures are depicted in surface representation. Homologous subunits are indicated in the table and colored accordingly. c The specific regions of ASFV RNAP are highlighted on the structure, while the remaining conserved regions are depicted as transparent gray surfaces.

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