Fig. 1: Longitudinal cortical gray matter volume trajectory across pregnancy and postpartum (N = 179). | Nature Communications

Fig. 1: Longitudinal cortical gray matter volume trajectory across pregnancy and postpartum (N = 179).

From: Pregnancy entails a U-shaped trajectory in human brain structure linked to hormones and maternal attachment

Fig. 1

Longitudinal changes were derived from the group x session2 fixed effect term of the adjusted linear mixed effect model: Cortical GM Volume ∼ Group + Session + Session2 + Group*Session + Group*Session2 + eTIV + Age + Euler + Inter-session Interval + (1 ∣ participant ID). A Mean percentage of cortical GM volume change per group and session in relation to the baseline (i.e., Session 1 - Pre-pregnancy Session). Error bars correspond to 95% confidence intervals around the sample’s mean at each experimental group and session, respectively. The gray shading corresponds to the pregnancy period. B Vertex-wise signed effect size maps (ηp2) of the group x session2 interaction (q value < 0.05). Indicating larger quadratic effects (red) and smaller quadratic effects (blue) in gestational mothers than in nulliparous or non-gestational mothers. Signed effect size maps were projected to the inflated fsaverage template provided by the FreeSurfer software. Colors were collapsed to ±0.14, which indicated a large effect size. Gest, gestational mothers; nGest, non-gestational mothers; Null, nulliparous women.

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