Fig. 4: The remote silylation reaction of internal alkenes with SCBs.
From: Enantioselective construction of silicon-stereogenic vinylsilanes from simple alkenes
a Reactions were carried out by using [Rh(cod)OMe]2 (5 mol%), L26 (11 mol%), 1 (0.4 mmol), 2 (0.2 mmol), Et3SiH (50 mol%) and LiOtBu (3.0 eq) in n-Heptane (0.3 M) for 48 h. Isolated yields after chromatography are shown. The E/Z were determined by 1HNMR. Enantiomeric ratio (er) was determined by chiral HPLC on commercial columns. b NaBH4 (1.0 eq) instead of Et3SiH (50 mol%). c L26-Rh-H (5 mol%) was used.
