Fig. 3: The separate continuous-flow modules for synthesis of 9 from 11. | Nature Communications

Fig. 3: The separate continuous-flow modules for synthesis of 9 from 11.

From: Flow chemistry-enabled asymmetric synthesis of cyproterone acetate in a chemo-biocatalytic approach

Fig. 3

a The ReM2-catalyzed Δ1-dehydrogenation of 11 into 10 in flow. b The two-step sequential-flow synthesis of 9 via ethynylation/Rupe rearrangement. The reactor I OAR model in a was drawn using AutoCAD. OAR Oscillation agitate reactor, PTFE Polytetrafluoroethylene, DCE Dichloroethane, HMPA Hexamethylphosphoramide, MFC Mass flow controller.

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