Fig. 6: Cell specific expression of TGF-β mRNA-IAJD34 in the lung over time. | Nature Communications

Fig. 6: Cell specific expression of TGF-β mRNA-IAJD34 in the lung over time.

From: Targeted delivery of TGF-β mRNA to murine lung parenchyma using one-component ionizable amphiphilic Janus Dendrimers

Fig. 6

Empty IAJD34 or 10 μg TGF-β mRNA-IAJD34 were delivered to BALB/c mice, and lung tissues were evaluated for TGF-β protein expression at 4, 24, and 48 h post-injection. Lung tissues was stained for TGF-β or IgG control via immunohistochemistry. Representative IHC images are shown. The slides are at 100x magnification, and the scale bars presented 100 µm. Increases in TGF-β protein expression were observed in the TGF-β mRNA-IAJD34 group through immunohistochemical staining from 4 to 48 h. The experiment was repeated 2 independent times. Scale bar = 100 µm.

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