Table 1 The baseline clinical characteristics of patients
Subgroup | ARR group (n = 499) | VSSR group (n = 244) | P-value | ||
---|---|---|---|---|---|
n or mean | % or σ | n or mean | % or σ | ||
Preoperative data | |||||
DeBakey | 0.299 | ||||
I | 364 | 72.95% | 169 | 69.26% | |
II | 135 | 27.05% | 75 | 30.74% | |
Age(years) | 60.09 | 7.64 | 54.99 | 2.54 | <0.001 |
BMI | 26.78 | 3.14 | 25.03 | 3.31 | 0.001 |
Sex | 0.096 | ||||
Male | 319 | 63.93% | 171 | 70.08% | |
Female | 180 | 36.07% | 73 | 29.92% | |
Race(Asian) | 499 | 100.00% | 244 | 100.00% | / |
Education level | 0.532 | ||||
Master degree or above | 4 | 0.80% | 0 | 0.00% | |
Undergraduate course | 56 | 11.22% | 24 | 9.84% | |
Junior college | 106 | 21.24% | 58 | 23.77% | |
Secondary and high schools | 146 | 29.26% | 66 | 27.05% | |
Junior high school and below | 187 | 37.47% | 96 | 39.34% | |
History of smoking | 0.159 | ||||
One cigarette a few days | 13 | 2.61% | 6 | 2.46% | |
One cigarette a day | 15 | 3.01% | 8 | 3.28% | |
2–3 cigarettes a day | 20 | 4.01% | 9 | 3.69% | |
4-10 cigarettes a day | 35 | 7.01% | 15 | 6.15% | |
10-20 cigarettes a day | 231 | 46.29% | 106 | 43.44% | |
More than 20 cigarettes a day | 51 | 10.22% | 22 | 9.02% | |
History of alcohol intake | 170 | 34.07% | 88 | 36.07% | 0.592 |
Hypertension | 414 | 82.97% | 210 | 86.07% | 0.267 |
Diabetes | 56 | 11.22% | 21 | 8.61% | 0.254 |
Chronic kidney diseases | 81 | 16.23% | 22 | 9.02% | 0.007 |
Peripheral vascular diseases | 45 | 9.02% | 11 | 4.51% | 0.037 |
Cerebrovascular diseases | 59 | 11.82% | 8 | 3.28% | <0.001 |
LVEF | 52.85 | 5.97 | 53.15 | 6.1 | 0.527 |
Marfan syndrome | 34 | 6.81% | 7 | 2.87% | <0.001 |
Malperfusion syndrome | 88 | 17.64% | 47 | 19.26% | 0.613 |
Brain | 12 | 2.40% | 5 | 2.05% | |
Coronary artery | 16 | 3.21% | 9 | 3.69% | |
Renal | 23 | 4.61% | 10 | 4.10% | |
Superior mesenteric artery | 2 | 0.40% | 2 | 0.82% | |
Lower extremity | 35 | 7.01% | 21 | 8.61% | |
Coronary Artery Stenosis | 0.477 | ||||
Moderate(50–70%) | 18 | 3.61% | 6 | 2.46% | |
Severe(>70%) | 17 | 3.41% | 9 | 3.69% | |
Aortic regurgitation | <0.001 | ||||
No or Mild | 82 | 16.43% | 137 | 56.15% | |
Moderate | 219 | 43.89% | 82 | 33.61% | |
Severe | 198 | 39.68% | 25 | 10.25% | |
Aortic root diameter(mm) | 44.47 | 4.48 | 42.52 | 4.52 | <0.001 |
Bicuspid aortic valve | 65 | 13.03% | 37 | 15.16% | 0.001 |
Moderate/severe pericardial effusion | 101 | 20.24% | 48 | 19.67% | 0.856 |
Preoperative shock(systolic blood pressure <80 mmHg) | 34 | 6.81% | 14 | 5.74% | 0.636 |
Intraoperative data | |||||
Operatig Time(min) | 306.89 | 70.38 | 315.76 | 63.58 | 0.097 |
CPBT(min) | 181.59 | 45.05 | 186.96 | 43.27 | 0.122 |
ACC (min) | 117.56 | 18.21 | 123.88 | 18.68 | <0.001 |
Concomitant procedures | |||||
Partial aortic arch replacement | 123 | 24.65% | 70 | 28.69% | 0.248 |
Complete aortic arch replacement | 326 | 65.33% | 164 | 67.21% | 0.611 |
CABG | 15 | 3.01% | 9 | 3.69% | 0.661 |
TVP | 14 | 2.81% | 12 | 4.92% | 0.235 |
MVP | 17 | 3.41% | 13 | 5.33% | 0.143 |
Blood transfusion | |||||
Erythrocytes (U) | 4.17 | 2.19 | 3.88 | 2.01 | 0.084 |
Cryoprecipitate (U) | 0.57 | 0.47 | 0.56 | 0.46 | 0.914 |
Plasma (U) | 556.99 | 341.26 | 596.31 | 350.44 | 0.144 |
Postoperative characteristics and Outcomes | |||||
Neurological deficits | 73 | 14.63% | 30 | 12.30% | 0.43 |
Renal insufficiency | 133 | 26.65% | 59 | 24.18% | 0.532 |
Low cardiac output syndrome | 12 | 2.40% | 10 | 4.10% | 0.249 |
Tracheostomy | 77 | 15.43% | 39 | 15.98% | 0.831 |
Sepsis | 67 | 13.43% | 28 | 11.48% | 0.485 |
Hepatic dysfunction | 115 | 23.05% | 58 | 23.77% | 0.854 |
Respiratory dysfunction | 39 | 7.82% | 17 | 6.97% | 0.768 |
Reintubation | 32 | 6.41% | 13 | 5.33% | 0.626 |
Stroke | 19 | 3.81% | 8 | 3.28% | 0.717 |
Endocarditis | 11 | 2.20% | 6 | 2.46% | 0.827 |
Reintervention for | 70 | 14.03% | 41 | 16.80% | 0.319 |
Spontaneous hemorrhage | 10 | 2.00% | 10 | 4.10% | |
Distal anastomotic fistula | 9 | 1.80% | 2 | 0.82% | |
Endocarditis | 36 | 7.21% | 3 | 1.23% | |
Aortic regurgitation(Moderate or Severe) | 12 | 2.40% | 18 | 7.38% | |
Aortic stenosis(Moderate or Severe) | 0 | 0.00% | 2 | 0.82% | |
Recurrent aortic dissection | 3 | 0.60% | 6 | 2.46% | |
ICU stay (days) | 9.29 | 10.50 | 8.84 | 9.84 | 0.595 |
Hospitalization time (day) | 20.68 | 9.84 | 19.52 | 9.73 | 0.129 |
Death rate | |||||
In-hospital mortality | 38 | 7.62% | 26 | 10.66% | 0.165 |
Overall mortality | 152 | 30.46% | 62 | 25.41% | 0.093 |