Table 2 Logistic regression analysis of confounding factors for the Selection of Aortic Root Replacement (ARR)
Subgroup | Univariate | Multivariate | ||
---|---|---|---|---|
OR (95% CI) | P-value* | OR (95% CI) | P-value | |
DeBakey | ||||
I | REF | |||
II | 0.836(0.597-1.170) | 0.295 | ||
Age(years) | 1.247(1.195-1.301) | <0.001 | 1.238(1.179-1.299) | <0.001 |
BMI | 1.178(1.121-1.238) | <0.001 | 1.234(1.150-1.324) | <0.001 |
Sex | ||||
Male | REF | |||
Female | 0.757(0.544-1.052) | 0.097 | ||
Race(Asian) | / | / | ||
Education level | 1.043(0.899-1.210) | 0.577 | ||
Master degree or above | ||||
Undergraduate course | ||||
Junior college | ||||
Secondary and high schools | ||||
Junior high school and below | ||||
History of smoking | ||||
One cigarette a few days | 0.793(0.290-2.170) | 0.651 | ||
One cigarette a day | 0.916(0.372-2.259) | 0.849 | ||
2–3 cigarettes a day | 0.773(0.335-1.781) | 0.546 | ||
4–10 cigarettes a day | 0.736(0.378-1.433) | 0.368 | ||
10–20 cigarettes a day | 0.788(0.549-1.132) | 0.197 | ||
More than 20 cigarettes a day | 0.741(0.418-1.314) | 0.305 | ||
History of alcohol intake | 1.092(0.793-1.504) | 0.591 | ||
Hypertension | 1.268(0.824-1.951) | 0.28 | ||
Diabetes | 0.745(0.440-1.261) | 0.745 | ||
Chronic kidney diseases | 1.955(1.188-3.219) | 0.008 | 1.025(0.338-3.102) | 0.966 |
Peripheral vascular diseases | 2.100(1.066-4.135) | 0.032 | 1.219(0.137-4.515) | 0.998 |
Cerebrovascular diseases | 3.956(1.859-8.418) | <0.001 | 1.335(0.247-3.936) | 0.974 |
LVEF | 0.992(0.967-1.017) | 0.527 | ||
Marfan syndrome | 11.380(4.965-26.081) | <0.001 | 19.639(6.261-61.602) | <0.001 |
Malperfusion syndrome | 1.114(0.752-1.650) | 0.589 | ||
Brain | ||||
Coronary artery | ||||
Renal | ||||
Superior mesenteric artery | ||||
Lower extremity | ||||
Coronary Artery Stenosis | ||||
No or Mild | REF | |||
Moderate(50–70%) | 0.668(0.262-1.706) | 0.399 | ||
Severe(>70%) | 1.061(0.466-2.418) | 0.888 | ||
Aortic regurgitation | ||||
Mild | 1.037(0.624-1.723) | 0.888 | REF | |
Moderate | 0.274(1.166-1.43) | <0.001 | 3.616(1.877-6.966) | <0.001 |
Severe | 3.098(2.077-4.621) | <0.001 | 18.712(9.554-36.648) | 0.001 |
Aortic root diameter(mm) | 1.100(1.062-1.140) | <0.001 | 1.115(1.062-1.172) | <0.001 |
Bicuspid aortic valve | 2.115(1.385-3.229) | 0.001 | 6.075(3.121-11.824) | <0.001 |
Moderate/severe pericardial effusion | 0.965(0.657-1.417) | 0.856 | ||
Preoperative shock(systolic blood pressure <80 mmHg) | 0.832(0.438-1.582) | 0.576 | ||
ACC (min) | 0.982(0.974-0.990) | <0.001 | 0.976(0.965-0.987) | <0.001 |