Fig. 6: SIMO reveals spatial regulation patterns in the mouse cerebral cortex.
From: Spatial integration of multi-omics single-cell data with SIMO
a The average DNA methylation activity, specific to each cell type, is graphically represented alongside the mean log-fold change in expression of the corresponding gene. Statistical analysis was performed using the two-sided PCC test. These plots uncover relationships that display significant correlations. b The dot plot shows the results of module analysis, and the color of the dots is defined according to the module to which they belong. c Spatial regulation modules of Layer5a cells were identified using SIMO. d SIMO maps of the activity score of the gene expression within modules of Layer5a cells. e Violin plots of the activity score of the gene expression within modules of Layer5a cells. f SIMO maps of the activity score of the DNA methylation within modules of Layer5a cells. g Violin plots of the activity score of the DNA methylation within modules of Layer5a cells.
