Table 1 Baseline characteristics of the HF population by triglyceride categories
Baseline characteristics | Total | Triglyceride levels (mmol/L) | ||||||
---|---|---|---|---|---|---|---|---|
<0.8 | 0.8–1.0 | 1.0–1.2 | 1.2–3.0 | 3.0–5.7 | ≥5.7 | P-value | ||
No. | 1,27,124 | 26,286 | 22,403 | 20,119 | 53,731 | 4143 | 442 | |
Demographics | ||||||||
Age (mean ± SD, years) | 71.4 ± 12.2 | 73.5 ± 11.7 | 72.6 ± 12.0 | 71.8 ± 12.2 | 70.2 ± 12.2 | 65.7 ± 12.8 | 63.2 ± 12.2 | <0.001 |
Sex (Male, %) | 65,869 (51.8) | 15,499 (61.3) | 14,032 (55.6) | 5990 (52.5) | 28,924 (46.7) | 1217 (42.2) | 207 (46.8) | <0.001 |
Smoking (%) | 7870 (6.2) | 2334 (9.2) | 1792 (7.1) | 681 (6.0) | 2948 (4.8) | 99 (3.4) | 16 (3.6) | <0.001 |
Alcohol (%) | 1577 (1.2) | 296 (1.2) | 323 (1.3) | 143 (1.3) | 733 (1.2) | 70 (2.4) | 12 (2.7) | <0.001 |
Comorbidities | ||||||||
Hypertension (%) | 56,780 (44.7) | 10,238 (40.5) | 10,689 (42.4) | 4863 (42.6) | 29,189 (47.2) | 1552 (53.8) | 249 (56.3) | <0.001 |
Diabetes (%) | 38,504 (30.3) | 5514 (21.8) | 6332 (25.1) | 3175 (27.8) | 21,804 (35.2) | 1439 (49.8) | 240 (54.3) | <0.001 |
Obesity (%) | 1985 (1.6) | 203 (0.8) | 279 (1.1) | 169 (1.5) | 1216 (2.0) | 100 (3.5) | 18 (4.1) | <0.001 |
Stroke (%) | 15,092 (11.9) | 3040 (12.0) | 3127 (12.4) | 1353 (11.9) | 7199 (11.6) | 325 (11.3) | 48 (10.9) | 0.035 |
Anemia (%) | 22,829 (18.0) | 4861 (19.2) | 4512 (17.9) | 1931 (16.9) | 10,878 (17.6) | 551 (19.1) | 96 (21.7) | <0.001 |
CAD (%) | 47,047 (37.0) | 8170 (32.3) | 9005 (35.7) | 4214 (36.9) | 24,289 (39.2) | 1170 (40.5) | 199 (45.0) | <0.001 |
PVD (%) | 16,814 (13.2) | 3182 (12.6) | 3404 (13.5) | 1551 (13.6) | 8210 (13.3) | 400 (13.9) | 67 (15.2) | 0.014 |
Dyslipidaemia (%) | 18,220 (14.3) | 2506 (9.9) | 3046 (12.1) | 1502 (13.2) | 10,342 (16.7) | 696 (24.1) | 128 (29.0) | <0.001 |
AF (%) | 33,431 (26.3) | 8944 (35.4) | 7510 (29.8) | 3088 (27.1) | 13,390 (21.6) | 435 (15.1) | 64 (14.5) | <0.001 |
Cirrhosis (%) | 1057 (0.8) | 256 (1.0) | 227 (0.9) | 95 (0.8) | 451 (0.7) | 23 (0.8) | 5 (1.1) | 0.001 |
CKF (%) | 13,903 (10.9) | 2109 (8.3) | 2242 (8.9) | 1119 (9.8) | 7789 (12.6) | 541 (18.7) | 103 (23.3) | <0.001 |
Other CKD (%) | 27,524 (21.7) | 4218 (16.7) | 4591 (18.2) | 2259 (19.8) | 15,262 (24.7) | 1019 (35.3) | 175 (39.6) | <0.001 |
Cancer (%) | 12,135 (9.5) | 2571 (10.2) | 2493 (9.9) | 1025 (9.0) | 5739 (9.3) | 270 (9.4) | 37 (8.4) | <0.001 |
Rheumatism (%) | 7615 (6.3) | 1444 (6.1) | 1420 (6.0) | 617 (5.7) | 3888 (6.6) | 207 (7.5) | 39 (9.2) | <0.001 |
Parkinson (%) | 1197 (1.0) | 278 (1.2) | 252 (1.1) | 92 (0.9) | 561 (1.0) | 13 (0.5) | 1 (0.2) | 0.001 |
Depression (%) | 2223 (1.7) | 337 (1.3) | 381 (1.5) | 189 (1.7) | 1202 (1.9) | 87 (3.0) | 27 (6.1) | <0.001 |
Sleep apnea (%) | 4830 (3.8) | 650 (2.6) | 777 (3.1) | 405 (3.6) | 2777 (4.5) | 188 (6.5) | 33 (7.5) | <0.001 |
Drugs | ||||||||
Aspirin (%) | 78,676 (61.9) | 15,312 (60.6) | 15,720 (62.3) | 7189 (63.0) | 38,443 (62.1) | 1745 (60.4) | 267 (60.4) | <0.001 |
ACEI (%) | 36,934 (29.1) | 7299 (28.9) | 7107 (28.2) | 3185 (27.9) | 18,302 (29.6) | 892 (30.9) | 149 (33.7) | <0.001 |
ARB (%) | 11,323 (8.9) | 1956 (7.7) | 2044 (8.1) | 985 (8.6) | 5914 (9.6) | 374 (13.0) | 50 (11.3) | <0.001 |
Beta blocker (%) | 42,420 (33.4) | 6939 (27.5) | 7622 (30.2) | 3645 (32.0) | 22,681 (36.6) | 1315 (45.5) | 218 (49.3) | <0.001 |
CCB (%) | 48,600 (38.2) | 8543 (33.8) | 9104 (36.1) | 4212 (36.9) | 25,264 (40.8) | 1287 (44.6) | 190 (43.0) | <0.001 |
Diuretics (%) | 38,689 (30.4) | 7448 (29.5) | 7105 (28.2) | 3311 (29.0) | 19,567 (31.6) | 1073 (37.2) | 185 (41.9) | <0.001 |
Statin (%) | 30,074 (23.7) | 5175 (20.5) | 5543 (22.0) | 2656 (23.3) | 15,679 (25.3) | 846 (29.3) | 175 (39.6) | <0.001 |
Insulin (%) | 9979 (7.8) | 1190 (4.7) | 1406 (5.6) | 727 (6.4) | 6003 (9.7) | 538 (18.6) | 115 (26.0) | <0.001 |
Other anti-DM drugs (%) | 25,921 (20.4) | 3756 (14.9) | 4238 (16.8) | 2163 (19.0) | 14,652 (23.7) | 949 (32.9) | 163 (36.9) | <0.001 |
Lipid profile | ||||||||
Total cholesterol (mean ± SD, mmol/L) | 4.42 (1.18) | 3.86 (0.97) | 4.15 (1.00) | 4.31 (1.04) | 4.71 (1.19) | 5.53 (1.48) | 6.23 (1.75) | <0.001 |
LDL-C (mean ± SD, mmol/L) | 2.58 (1.00) | 2.16 (0.78) | 2.43 (0.86) | 2.57 (0.91) | 2.81 (1.05) | 2.84 (1.34) | 2.66 (1.42) | <0.001 |
HDL-C (mean ± SD, mmol/L) | 1.32 (0.55) | 1.45 (0.49) | 1.37 (0.51) | 1.32 (0.49) | 1.25 (0.57) | 1.13 (0.73) | 1.11 (0.73) | <0.001 |