Table 1 Associations of COL1/LOX expression (liver stiffness) with clinicopathologic characteristics in HCC tissues

Age

0.2330

 ≤ 59

11

7

 > 59

13

17

Gender

0.7115

 Male

19

20

 Female

5

4

HBsAg

0.7313

 Negtive

6

5

 Positive

18

19

ALT (U/L)

0.0860

 ≤ 40

16

21

 > 40

8

3

AST (U/L)

0.5510

 ≤ 35

14

16

 > 35

10

8

AFP (ng/mL)

0.7453

 ≤ 20

17

18

 > 20

7

6

Tumor size (cm)

0.1824

 < 3

8

4

 ≥ 3

16

20

Microvascular invasion

0.7679

 No

10

9

 Yes

14

15

Tumor differentiation

0.0388

 Edmondson I–II

18

11

 III–IV

6

13

Tumor recurrence

0.0093

 No

16

7

 Yes

8

17

let-7d-5p expression

0.0209

 Low

16

8

 High

8

16

miR-365a-5p expression

0.0431

 Low

16

9

 High

8

15