Fig. 5: Patient microbiome profile is associated with overall survival. | Nature Communications

Fig. 5: Patient microbiome profile is associated with overall survival.

From: Improved overall survival in an anti-PD-L1 treated cohort of newly diagnosed glioblastoma patients is associated with distinct immune, mutation, and gut microbiome features: a single arm prospective phase I/II trial

Fig. 5

A The alpha-diversity of each patient’s pre-treatment fecal microbiome was determined and compared between patients with low (n = 9) versus high (n = 13) OS. The “box” shows the interquartile range (IQR) between the 25th and 75th percentiles, the “center line” marks the median, the “whiskers” extend to 1.5 times the IQR, and points beyond are outliers, with “minima” and “maxima” as the absolute lowest and highest values. Source data are provided as a Source Data file. B Delineation of the type and relative abundance of each species identified in each fecal microbiome between patients with low versus high OS. Source data are provided as a Source Data file. C Principal coordinate analysis of fecal microbiome beta-diversity in low versus high OS patients. Source data are provided as a Source Data file. D Prevalence of fecal microbiome bacterial species in patients with low vs. high OS. Source data are provided as a Source Data file.

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