Table 2 Hazard ratios (95%CIs) for mortality from major categories of diseases linked to per 10 μg/m3, SD, and IQR increases in NOx

From: Associations of long-term exposure to nitrogen oxides with all-cause and cause-specific mortality

ICD-10 code

ICD-10 chapter

Number of deaths

HRs (95%CIs)

10 μg/m3

SD (11.75 μg/m3)

IQR (14.16 μg/m3)

A00-Z99

All-cause mortality

44,090

1.036 (1.024, 1.049)

1.043 (1.028, 1.058)

1.052 (1.034, 1.070)

A00-R99

Non-accidental diseases

41,523

1.032 (1.019, 1.045)

1.038 (1.023, 1.054)

1.046 (1.028, 1.065)

V01-X59, Y85-Y86

Accidental death

641

1.001 (0.907, 1.106)

1.002 (0.891, 1.125)

1.002 (0.871, 1.153)

A00-B99

Infectious and parasitic

385

1.072 (0.944, 1.219)

1.086 (0.934, 1.262)

1.104 (0.921, 1.323)

C00-D48

Neoplasms

21,564

1.010 (0.993, 1.027)

1.012 (0.992, 1.032)

1.014 (0.990, 1.039)

D50-D89

Blood and immune-related diseases

99

1.004 (0.783, 1.286)

1.004 (0.751, 1.344)

1.005 (0.708, 1.428)

E00-E90

Endocrine, nutritional and metabolic diseases

531

1.077 (0.964, 1.203)

1.091 (0.958, 1.242)

1.111 (0.950, 1.299)

F00-F99

Mental and behavioural disorders

1123

1.096 (1.002, 1.199)

1.114 (1.002, 1.238)

1.138 (1.002, 1.293)

G00-G99

Nervous system

2695

0.976 (0.920, 1.036)

0.972 (0.907, 1.043)

0.967 (0.888, 1.052)

I00-I99

Circulatory system

9283

1.043 (1.015, 1.072)

1.051 (1.018, 1.085)

1.062 (1.022, 1.103)

J00-J99

Respiratory system

3189

1.139 (1.090, 1.190)

1.165 (1.107, 1.227)

1.202 (1.130, 1.280)

K00-K93

Digestive system

1747

1.057 (0.993, 1.124)

1.067 (0.992, 1.147)

1.081 (0.991, 1.180)

L00-L99

Skin and subcutaneous tissue

75

0.886 (0.618, 1.270)

0.867 (0.568, 1.325)

0.842 (0.505, 1.403)

M00-M99

Musculoskeletal system and connective tissue

251

1.092 (0.932, 1.280)

1.109 (0.920, 1.337)

1.133 (0.905, 1.419)

N00-N99

Genitourinary system

321

1.081 (0.928, 1.260)

1.096 (0.916, 1.312)

1.117 (0.900, 1.387)

Q00-Q99

Congenital malformations, deformations and chromosomal abnormalities

73

1.108 (0.822, 1.494)

1.128 (0.794, 1.603)

1.156 (0.758, 1.765)

R00-R99

Other symptoms, signs and abnormal findings

184

1.177 (1.003, 1.381)

1.211 (1.003, 1.462)

1.259 (1.004, 1.580)

V01-Y98

External causes of morbidity and mortality

1114

1.099 (1.029, 1.174)

1.117 (1.034, 1.207)

1.143 (1.041, 1.254)

  1. Time-varying Cox regression was used to assess the associations between NOx and mortality, with the adjustment of age, sex, ethnicity, body mass index, education, occupation, smoking status, alcohol consumption, physical activity, residential area, and household income. Two-sided P values less than 0.05 were considered as statistically significant. Bolded values denote P < 0.05.