Fig. 5: PGLYRP1 interacts with NOD2 and GEF-H1 in ER- and Golgi-associated compartments. | Nature Communications

Fig. 5: PGLYRP1 interacts with NOD2 and GEF-H1 in ER- and Golgi-associated compartments.

From: PGLYRP1-mediated intracellular peptidoglycan detection promotes intestinal mucosal protection

Fig. 5

a Western blot analysis of protein expression in BMDMs from wildtype, Arhgef2-/-, Pglyrp1-/-, and Nod2-/- mice. b Time course of protein interactions with GEF-H1 after GMTriP-K stimulation of BMDMs. c Analysis of protein interactions with PGLYRP1 or d NOD2 after GMTriP-K stimulation of BMDMs. e Input assessment of protein expression for the IPs in (c, d). f Assessment of protein interactions with GEF-H1 after stimulation with indicated immune stimuli. Representative experiments of at least three repeats are shown.

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