Fig. 8: PGLYRP1 mediated recognition of peptidoglycans in macrophages controls mucosal inflammation. | Nature Communications

Fig. 8: PGLYRP1 mediated recognition of peptidoglycans in macrophages controls mucosal inflammation.

From: PGLYRP1-mediated intracellular peptidoglycan detection promotes intestinal mucosal protection

Fig. 8

PGLYRP1 is required for detection of GMTriP-K. PGLYRP1 localizes to the endoplasmic reticulum and Golgi and interacts with NOD2 and GEF-H1 to induce the expression of immune regulators that regulate intestinal inflammation (Created in BioRender. Reinecker, H. (2025) https://BioRender.com/i55t156).

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