Fig. 6: The anti-tumor effect of Co-SAEs/HNCS in vitro. | Nature Communications

Fig. 6: The anti-tumor effect of Co-SAEs/HNCS in vitro.

From: NIR-triggering cobalt single-atom enzyme switches off-to-on for boosting the interactive dynamic effects of multimodal phototherapy

Fig. 6

a The cellular activity of Cal-33 cells under NIR-I condition, the data of each group were analyzed using t-test statistics. Data are shown as mean with SD (n = 3, biological replicates). b The concentration and cell viability curves of the cytotoxicity under different conditions. The data of each group were analyzed using One-way ANOVA statistics. “up” marks Co-SAEs/HNCS + NIR and Co-SAEs/HNCS + NIR + ICE group for statistical analysis, “down” marks Co-SAEs/HNCS + NIR and Co-SAEs/HNCS + NIR+Vc group for statistical analysis. Data are shown as mean with SD (n = 3, biological replicates). c The cell death in cells observed by CLSM under different conditions. d The apoptosis/necrosis detection semi-quantitative analyzed by FCM. e HSP70 expression under different conditions (n = 3, independent experimental replicates). (808 nm, 1 W/cm2, 10 mins). Scale bar: c, 200 µm. c, d, e Each experiment was repeated three times with similar results. Source data are provided as a Source Data file.

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