Table 2 Exposure information for visit 1 (n = 216) and visit 2 (n = 145) for the participants in the metabolomic-wide association study

From: Impact of prenatal phthalate exposure on newborn metabolome and infant neurodevelopment

Metabolite (ng/ml)

Visit 1 (8–14 weeks) n = 216

Visit 2 (24–30 weeks) n = 145

Fourth national report on human exposure to environmental chemicals (2015–2016)

Median (IQR)

GM

Median (IQR)

GM

Age \({\ge }\)20 GM

Non-Hispanic black GM

Monoethyl phthalate (MEP)

98 (44, 233)

103

81 (34, 180)

83.1

35.9

54.9

Mono-n-butyl phthalate (MBP)

11 (5, 20)

9.8

10 (5, 26)

9.2

9.36

10.9

Monoisobutyl phthalate (MiBP)

10 (4, 19)

8.8

8 (3, 16)

7.5

8.03

9.29

Monobenzyl phthalate (MBzP)

6 (2, 13)

5.7

5 (2, 11)

4.9

3.87

5.57

Mono-2-ethylhexyl phthalate (MEHP)

1.7 (0.6, 4.6)

1.7

2.4 (0.7, 5.0)

1.8

#

1.27

Mono-2-ethyl-5-oxohexyl phthalate (MEOHP)*

3.1 (1.7, 6.5)

3.3

3.7 (1.5, 7.1)

3.1

3.36

3.66

Mono-2-ethyl-5-hydroxyhexyl phthalate (MEHHP)*

5 (3, 11)

5.3

5 (2, 9)

4.2

5.40

5.96

Mono-2-ethly-5-carboxypentyl phthalate (MECPP)*

7 (4, 13)

8.1

6 (4, 11)

7.1

8.28

8.51

Sum of Di-2-ethylhexyl phthalate metabolites (\({{{\boldsymbol{\Sigma }}}}\)DEHP)

0.06 (0.03, 0.11)

0.07

0.06 (0.03, 0.11)

0.06

-

-

  1. Note: All phthalate metabolites were found in 100% of samples.
  2. *Secondary metabolite.
  3. GM geometric mean, # not calculated: proportion of results below the limit of detection was too high to provide a valid result, IQR interquartile range.
  4. Phthalate exposure metabolite levels (ng/ml) were compared to the Centers for Disease Control and Prevention’s Fourth National Report on Human Exposure to Environmental Chemicals (2015–2016)18. Atlanta African American Maternal-Child cohort, 2016–2018.