Fig. 2: Association of Rare Variant Burden with Lifespan.
From: Rare genetic associations with human lifespan in UK Biobank are enriched for oncogenic genes
Rare variant burden association with lifespan, considering loss-of-functions (A) and AlphaMissense pathogenic variants (B). Genes highlighted in red represent those not previously identified as significant in ref. 8. A gene-wide significance threshold of \(p\) = 7.4\(\times {10}^{-7}\) was applied.
