Fig. 1: Single-cell atlas identifies activation of the Myc program in ECs following cholestatic liver injury. | Nature Communications

Fig. 1: Single-cell atlas identifies activation of the Myc program in ECs following cholestatic liver injury.

From: Chenodeoxycholic acid modulates cholestatic niche through FXR/Myc/P-selectin axis in liver endothelial cells

Fig. 1

a UMAP visualization showing liver EC subtypes. GSEA of hallmark gene sets (b), enrichment of transcription factor motifs in ECs (c), and (d) Myc gene expression in ECs from different liver injury models. e Immunofluorescence (IF) staining of CD31 (green) and Myc (red) in liver tissue samples from different liver injury models as indicated. Representative images illustrate the findings from three independent biological experiments with similar results.

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