Fig. 3: Substrate scope.
From: Asymmetric reductive arylation and alkenylation to access S-chirogenic sulfinamides
a Scope of iodoarenes with sulfinylamine I. b Selected examples of iodoarenes with sulfinylamine IV. aReaction conditions: Ni(cod)2 (15 mol%), L5 (18 mol%), 2-31a (3.0 equiv., 0.3 mmol), I (1.0 equiv., 0.1 mmol), Zn dust (3.0 equiv., 0.3 mmol) in CH3CN (superdry, water ≤10 ppm, 0.1 M) at 40 oC for 5 days under N2 atmosphere; Isolated yields; E.r. values determined by chiral HPLC. bUsing L4 instead of L5. cReact for 5 days at 10 oC. dShortened to 3 days with 2-31a (1.0 equiv., 0.1 mmol) and IV (3.0 equiv., 0.3 mmol).
