Fig. 4: Substrate scope.
From: Asymmetric reductive arylation and alkenylation to access S-chirogenic sulfinamides
Reaction conditions: Co(dme)Br2 (10 mol%), L6 (12 mol%), 32-46a (2.0 equiv, 0.2 mmol), I (1.0 equiv., 0.1 mmol), In dust (3.0 equiv., 0.3 mmol), nBu4NBF4 (2.0 equiv., 0.2 mmol) and 3 Å MS (50 mg) in CH3CN (superdry, water ≤10 ppm, 0.5 M) at 20 oC for 5 days under N2 atmosphere; Isolated yields; E.r. values determined by chiral HPLC.
