Fig. 2: Comparison of ARG distribution and antimicrobial resistance levels in BSI-derived CC1-, CC5-, and CC8-MRSA lineages during 1994–2000 and 2019–2020. | Nature Communications

Fig. 2: Comparison of ARG distribution and antimicrobial resistance levels in BSI-derived CC1-, CC5-, and CC8-MRSA lineages during 1994–2000 and 2019–2020.

From: Staphylococcus aureus ST764-SCCmecII high-risk clone in bloodstream infections revealed through national genomic surveillance integrating clinical data

Fig. 2

a The number of antimicrobial-resistant genes (ARGs) per strain is shown, but duplicate ARG genes are not counted. The triangle in the box indicates mean, the box indicates the 25th and 75th percentiles, and the whiskers indicate the highest and the lowest values of the results. The line in the box indicates median. P-value (p) was calculated using the Student’s t-test. b Presence heatmap of major ARGs and quinolone resistance-determinant region (QRDR) mutations identified. The numbers in the heatmap columns are shown as percentages. *p < 0.05; ST5-II_1994-2000 vs. ST5-II_2019-2020. #p < 0.02; ST5-II_2019-2020 vs. ST764-II_2019-2020. P-value (p) was calculated using the χ2 test. c Antimicrobial susceptibility profiles of BSI-derived MRSA. The radar chart shows the resistance rates of isolates to MPIPC, CEZ, CMZ, GM, ABK, EM, CLDM, MINO, and LVFX in 1994–2000 and 2019–2020.

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