Fig. 2: World maps showing the allele frequency distribution of the four FRS3 missense variants identified in the study.
From: Missense variants in FRS3 affect body mass index in populations of diverse ancestries
Low allele frequencies are shown in light color, while higher frequencies are depicted in dark color. Gray indicates that zero participants reported being born in that country or region. Frequencies shown are for UK Biobank participants with origins in that region, except for Finland, for which the frequency in FinnGen was used. a p.Glu115Lys (rs773053137-T) is only found in Finland. b p.Pro137Arg (rs146730626-C) is predominantly found in East Asia but is present at lower frequencies in South Asia and the Indian Ocean. c p.Pro172Leu (rs74687105-A) is predominantly found in populations of African ancestry and is most common in Southern Africa. d p.Arg316Gln (rs35744673-T) is broadly distributed, but most common in populations of European ancestry. This figure was created with Natural Earth.
