Fig. 2: Volcano plots of individual protein associations with inflammatory bowel disease and its subtypes in UK Biobank. | Nature Communications

Fig. 2: Volcano plots of individual protein associations with inflammatory bowel disease and its subtypes in UK Biobank.

From: Associations of 2923 plasma proteins with incident inflammatory bowel disease in a prospective cohort study and genetic analysis

Fig. 2

Unadjusted any variable in estimating the hazard ratios of each protein for (a) inflammatory bowel disease (IBD), (d) Crohn’s disease (CD), and (g) ulcerative colitis (UC). Adjusted for age, sex, assessment center, education, employment status, household income, and TDI in estimating the hazard ratios of each protein for (b) IBD, (e) CD, and (h) UC. Additional adjusted for smoking status, alcohol consumption, PA, healthy diet, sleep during, and BMI in estimating the hazard ratios of each protein for (c) IBD, (f) CD, and (i) UC. Red, blue, and gray dots denote positive significant, inverse significant, and nonsignificant associations, respectively. FDR false discovery rate, HR hazard ratio. Source data are provided as Supplementary Data 1 and Source Data file.

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